Molecular Details
DICL_CP_0306908
- nitroxyl
Basic Molecular Information
Basic Information
DICL ID
DICL_CP_0306908
PubChem CID
Molecular Formula
HNO Molecular Weight
31.014 g/mol
Synonyms/Alias
[Nitroxyl; Nitrosyl hydride; aza; 14332-28-6; oxidanimine; GFQ4MMS07W; CHEBI:84879; HNO; Nitronous oxide; Stickmonoxyd [German]; Oxyde nitrique [French]; UNII-GFQ4MMS07W; Bioxyde dazote [French]; RCRA...
InChI Key
ODUCDPQEXGNKDN-UHFFFAOYSA-N
InChI
InChI=1S/HNO/c1-2/h1H
IUPAC Name
nitroxyl
CAS Number
N/A (Not available)
Structure Information
Chemical Structure Visualization
SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF
2 1 0 0 0 0 0 0 0 0999 V2000
-0.7500 0.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
0.7500 -0.0000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
1 2 2 0
M...
Experimental Data
Activity Data
Target Ion Channel
A-type voltage-gated potassium channel KCND3
Uniprot Accession Number
Function
Inhibitor
Species
Homo sapiens (Human)
IC50
IC50: 375 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)
Experimental Conditions
pH
pH 7.4
Holding Potential
−80 to 50 mV mV
Temperature
21−23 °C
Test Method
Patch-clamping
Test Species
CHO cell (Chinese hamster ovary cell)
Binding Information
Binding Site
Not specified
Binding Site Residue
Not specified
Disease Information
Related Disease
Not specified
References
Computed Properties
Heavy Atom Count
2
Rotatable Bonds
0
logP
0.3316
Complexity
6.0867
TPSA (Ų)
40.92
H-Bond Donors
1
H-Bond Acceptors
2
Ring Count
0